What product is right for my pet?
The chart below will help you understand the differences between the active ingredients in our liver products so you can better discuss the needs of your pet with your veterinarian.
Your pet's veterinarian is the person most qualified to assess your pet's needs.
SAMe (S-Adenosylmethionine)
As found in Denamarin and Denosyl
Increases levels of glutathione which is an important compound for liver health. Dogs and cats make glutathione from SAMe.
Although SAMe is naturally produced by the liver, its production is decreased when the liver is compromised1 which leads to less glutathione. A study of dogs and cats with various liver function problems reported that many had low liver glutathione levels.2
SAMe is found in Denamarin and Denosyl.
Research is looking into dog aging and associated decreases in levels of S-Adenosylmethionine (SAMe) in cerebrospinal fluid, which surrounds the brain.
Age related brain issues include confusion or personality changes often expressed through being less social.
Both Denosyl and Denamarin provide SAMe in a stabilized form to help with brain health and act as a neuroprotector. The silybin in Denamarin also reaches the brain tissue and may act as additional support to maintain a healthy oxidative balance.
Silybin
As found in Denamarin, Marin and Marin for Cats
Silybin (derived from milk thistle) supports oxidative balance and helps the flow of bile through the liver. Bile is important in aiding digestion and nutrient absorption.
Silybin may also support levels of glutathione which is an important compound for liver health.
The exclusive silybin found in Denamarin, Marin and Marin for Cats is complexed with phosphatidylcholine which has been shown to increase absorption compared to standardized milk thistle extracts. Absorption of the silybin-phosphatidylcholine complex has been demonstrated in both dogs and cats.
Silybin is found in Denamarin, Marin and Marin for Cats.
Vitamin E and Zinc
As found in Marin. Zinc is not found in Marin for Cats.
Vitamin E is an antioxidant that has been shown to help protect liver function.
Zinc supplementation may be beneficial in dogs with long-term decreased liver function as these dogs often have low liver zinc levels. Zinc participates in many enzymatic reactions within the body, and any deficiency may have harmful effects. Zinc is not in Marin for Cats as deficiencies have not been noted in cats.
Vitamin E is found in Marin and Marin for Cats. Zinc is found in Marin for Dogs.
L-Carnitine
As found in Quinicarn.
L-Carnitine is a fatty acid carrier that plays a role in fat oxidation in the body. The requirements of L-Carnitine in cats and dogs are increased in conditions of physiological and metabolic stress.
L-Carnitine is found in Quinicarn.
REFERENCES
1. Center SA. Proceedings of the 18th ACVIM, Seattle, WA, 2000; 550-552.
2. Center SA, Warner KL, Erb HN. Am J Vet Res 2002; 63(8):1187-1197.