How does Marin work?

Marin provides support for the liver with silybin and vitamin E. Marin also contains zinc for additional benefit.

The chart below illustrates that the silybin in Marin which is in a phosphatidylcholine complex has increased bioavailability, reaching levels up to 4 times more than that seen with 80% standardized milk thistle extracts(silymarin).

Plasma levels of silybin in dogs after oral administration of SPC* versus oral administration of silymarin
Each is given as one oral dose equivalent to 16 mg/kg body weight of silybin.

Filburn CR, Kettenacker R, Griffin D. Safety and bioavailability in beagles of zinc and vitamin E combined with silybin and phosphatidylcholine. Inten J Appl Res Med 2006;4(4):326-334.

*Silybin-phosphatidylcholine complex

Marin is available in a convenient chewable formulation which provides another option for those pets requiring on-going liver support.

Marin, Denosyl, and Denamarin support the liver through differing actions and may be used individually or in combination depending on your pet’s needs. Your veterinarian can advise you on the best way to support your pet's liver.

Administration: Marin Tablets

Marin For Dogs is formulated in a tasty chewable tablet. Tablets are scored for ease of administration. Recommended administration amounts are provided below.

Marin For Dogs Daily* Administration Guide

Marin For Dogs
Body Weight	For Small to Medium Dogs	For Large Dogs
Up to 10 lbs	1/4 tablet	-
10-19 lbs	1/2 tablet	-
20-35 lbs	1 tablet	-
36-54 lbs	-	1/2 tablet
55-99 lbs	-	1 tablet
Over 100 lbs	-	1 1/2 tablets

*Tablets should be given on a full stomach.

Storage

Store in a cool dry place. Keep tablets in bottle until used.

Active Ingredients
Each tablet contains:	For Small to Medium Dogs	For Large Dogs
Vitamin E (As d-α tocopheryl acetate)	105 IU	300 IU
Silybin A+B	24 mg*	70 mg*
Zinc (as zinc gluconate)	17 mg	45 mg

* In a phosphatidylcholine complex to increase bioavailability.